Study Shows Bleeding Risks Higher With Xarelto Than Competing Drugs

Xarelto (rivaroxaban), a direct oral anticoagulant (DOAC) made by Bayer and Johnson & Johnson subsidiary Janssen Pharmaceuticals, is used to prevent dangerous blood clots in patients who've had total hip or knee replacement surgeries. Sometime the drug works too well, triggering internal bleeding that can be life-threatening and even fatal. While any anticoagulant has the potential to cause internal bleeding in some patients, a 2017 study conducted by researchers at the Mayo Clinic and reported in the medical journal Gastroenterology found that Xarelto had the highest bleeding rates of any drug in its class. Xarelto causes significant bleeding

The five-year Mayo Clinic study analyzed data from approximately 57,000 non-valve atrial fibrillation patients who experienced gastrointestinal bleeding while being treated with Xarelto, Pradaxa (dabigatran), or Eliquis (apixaban)—all of which are in the DOAC class of medications. Researchers found that Xarelto caused more instances of gastrointestinal bleeding than Eliquis or Pradaxa, and that all three DOACs increased the risk of serious internal bleeding for patients 75 and older.

DOACs vs. Traditional Anticoagulants

In the world of anticoagulant medications, DOACs such as Xarelto are the “new kids on the block”—developed as alternatives to old-school blood thinners like warfarin. Xarelto and other next-generation medications quickly found popularity among doctors and patients who were all too eager to avoid the dietary restrictions and regular blood monitoring required by older anticoagulants.

However, for all its benefits, Xarelto has a seriously significant downside: There isn't a safe, reliable and FDA-approved way to reverse its blood-thinning effects. Doctors can sometimes mitigate the drug's effects with dialysis, but this process is time consuming and often ineffective. The lack of an effective Xarelto antidote has led many patients who've experienced life-threatening bleeding events to file a lawsuit against its manufacturers.

Are You Considering a Xarelto Bleeding Lawsuit?

If you or someone you love suffered serious internal bleeding while taking Xarelto, the knowledgeable attorneys at Holton Law Firm can help you pursue compensation for your injuries. Contact our Memphis law office today to set up a free initial consultation to discuss the details of your potential Xarelto bleeding case.


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